229 startups in this batch
The W20 cohort was the final batch to experience a physical YC before the world locked down, defined by a focus on hyper-local logistics, emerging market infrastructure, and B2B sales orchestration. It was an era where "software eating the world" meant digitizing physical supply chains and professionalizing the messy middle of global trade.
This batch proved that last-mile delivery in LatAm and career placement in India were massive, underserved markets ripe for platformization. They validated the demand for Revenue Excellence tools that move beyond simple CRMs to active sales collaboration, and showed that synthetic biology could finally tackle "undruggable" targets through machine learning.
Many W20 startups struggled when the low-interest-rate environment vanished, revealing that high-burn operational models without massive margins were fragile. Builders today should learn that manual coordinationβeven when wrapped in a sleek SaaS UIβis no longer a moat; if the core value prop relies on human-heavy operations, it is a prime target for AI displacement.
The massive logistics and sales playbooks established by W20 are now prime for AI-agent takeovers. A solo founder can now rebuild a "Revenue Excellence" platform where autonomous agents handle the multi-threading, business case drafting, and financial governance that previously required an entire sales operations department.
We create activating antibodies to treat diseases others canβt.
Using CRISPR to find treatments for cancer and inflammation
Alloy is a platform for building and managing SaaS integrations
Altay develops disease-modifying therapies targeting transcriptionβ¦
We offer free software that automates bureaucracy for real-estateβ¦
Apartio offers Short Term Rentals for Business Travelers in Brazil
Transform your text data into a searchable knowledge graph
Avion builds and operates autonomous eVTOL drones that deliver vitalβ¦
BeGo Connects cargo shippers with truck suppliers in Mexico and US
A platform for fitness instructors to build their business andβ¦
borong is a SaaS-enabled marketplace that connects brands likeβ¦
A digital well-being program to help people prevent or manage chronicβ¦
BuildBuddy provides enterprise features for Bazel β the open sourceβ¦
CARUPI is the world's 1st managed P2P marketplace for used cars
E-commerce site where you can buy certified used-cars in Latin America
Cortex is the Internal Developer Portal eliminating βdeveloper taxββ¦
Crowdforce is an app that allows any local merchant in Africa,β¦
Datasaur builds a data labeling workforce management platform for NLP.
Datree prevents Kubernetes misconfigurations from reaching production
Deep Meditate is an app that helps you de-stress, sleep, andβ¦
Unified DevSecOps platform, helping developers ship good code.
Manage the words across your teamβs product from design to production.
AI app builder for internal tools. Build back-office software fasterβ¦
Helps enterprises train college CS students on essential job skills
We are developing a drug to burn calories and increase metabolismβ¦
Developing supersonic UAVs as a pathway to quiet supersonic flight
The easiest way to track, buy, and sell your companyβs tech β all inβ¦
Helping 100+ brands bring all quality and compliance operationsβ¦
India's first vegetable delivery service to restaurants with a hack
AI-powered gym and home workout planner that generates personalized plans, optimizes sets, reps, and weights based on user data.
Quickly build internal tools for your ops team's manual workflows
We are connecting every single Mexican to the financial system.
The next generation of induced-proximity medicines.
Glisten AI automatically categorizes and tags e-commerce product data using computer vision and natural language processing.
Marketplace enabling social commerce for brands and content creators.
AI-native direct booking infrastructure for global hospitality
Handl converts documents (invoices, income stabs, custom forms, etc.)β¦
We help job seekers quickly create resumes that get 2X more interviews
A talent acquisition software built for data-driven recruiting teams.
Homestead is a real estate development platform for homeowners
A developer experience platform that equips teams with tools to create exceptional customer experiences through superior documentation, API monitoring, and customizable developer dashboards.
We empower the worldβs hiring teams to grow engaged, high-performingβ¦
Jenfi provides revenue-based financing for digital businesses in Asia
Find culinary products and experiences from great makers everywhere
Implement streamlined Salesforce processes for agile GTM teams
AI-powered marketplace connecting gamers with professional players for coaching, carry services, and in-game companionship.
Modern egg freezing for half the cost in half the time with top docs
Modern & comprehensive health insurance plan for employees in India
Building an AI Health Insurance Agent.
Menten AI designs peptide and protein therapeutics using quantumβ¦
The Family AI - a copilot for parents to tackle the invisible load ofβ¦
Connect, Unify, Respond to any data, anywhere with human-levelβ¦
Robotic Automation for cancer diagnostics - Robotic Microscopes &β¦
The only work management platform for both Human and AI Employees
Multiverse is a web-based game creation system inspired by Dungeons &β¦
A DecisionOps platform that accelerates optimization AI teams
ML models automatically monitor business metrics and send alerts for abnormal drops or spikes.
College entrance test preparation App for students in Indonesia
A competitive community of the brightest students in the world
Pashi builds software to operate and optimize production lines.
The super simple stablecoin wallet with free transactions
Automated tooth cutting for dentists using imaging, AI and robotics
The best way to collect and analyze voice and video feedback
The social app for edge-of-culture communities
The single platform to analyze, test, observe, and deploy new features
Pulley helps founders and finance teams manage their equity and capβ¦
Dynamic sales materials that shape-shift based on the customers needs
Fullstack API and management platform for dashboards and reporting
The API to get recordings, transcripts, and metadata from meetings
Riya Collective is building the first community-driven globalβ¦
Robotire is automating vehicle maintenance for today and futureβ¦
Affordable mental self-care for all. Acquired by Headspace Health.
Low-cost blood glucose test strips scanned with a smartphone cameraβ¦
Enterprise software to quantify cost-effective decarbonizationβ¦
AI platform for retail merchandising that optimizes inventory placement, re-balancing, and fulfillment decisions to maximize revenues.
StayQrious helps kids in India learn through online group classes,β¦
AI that tells mining companies where to mine to maximize profits
Building modern payments, accounting and cashflow management toolsβ¦
AI-enabled automation of diagnostic radiology workflow and reporting.
Intelligence layer for internal communications and culture
The one-stop shop for mom-and-pop stores in Pakistan to buy inventory.
Long range, battery electric vertical take-off and landing aircraft.
Juno is ManusAI for controlling medical imaging& diagnostic device GUI
AI assistant that automates everyday tasks and streamlines workflows for professionals and businesses.
The Mercer Club is a subscription service that allows men to rentβ¦
TrueNorth gives truckers a single place to manage their business.
AI for R&D of consumer brands like P&G to develop better products
A no-code website builder with a Notion-like interface that enables users to build and publish websites in minutes using AI-powered defaults and templates.
Helping Dropshippers in Colombia run the business and increase sales
Volumetric builds living multicellular tissues with a focus on theβ¦
Whatnot is the largest livestream shopping platform in the U.S.
Route Optimisation platform for SMB in delivery & home services.
Generates synthetic training data for computer vision models using game engines and domain randomization.
Office management platform that optimizes your hybrid workplace