229 startups in this batch
The W20 cohort was the final batch to experience a physical YC before the world locked down, defined by a focus on hyper-local logistics, emerging market infrastructure, and B2B sales orchestration. It was an era where "software eating the world" meant digitizing physical supply chains and professionalizing the messy middle of global trade.
This batch proved that last-mile delivery in LatAm and career placement in India were massive, underserved markets ripe for platformization. They validated the demand for Revenue Excellence tools that move beyond simple CRMs to active sales collaboration, and showed that synthetic biology could finally tackle "undruggable" targets through machine learning.
Many W20 startups struggled when the low-interest-rate environment vanished, revealing that high-burn operational models without massive margins were fragile. Builders today should learn that manual coordination—even when wrapped in a sleek SaaS UI—is no longer a moat; if the core value prop relies on human-heavy operations, it is a prime target for AI displacement.
The massive logistics and sales playbooks established by W20 are now prime for AI-agent takeovers. A solo founder can now rebuild a "Revenue Excellence" platform where autonomous agents handle the multi-threading, business case drafting, and financial governance that previously required an entire sales operations department.
We create activating antibodies to treat diseases others can’t.
Using CRISPR to find treatments for cancer and inflammation
Alloy is a platform for building and managing SaaS integrations
Altay develops disease-modifying therapies targeting transcription…
Apartio offers Short Term Rentals for Business Travelers in Brazil
Avion builds and operates autonomous eVTOL drones that deliver vital…
A digital well-being program to help people prevent or manage chronic…
BuildBuddy provides enterprise features for Bazel — the open source…
E-commerce site where you can buy certified used-cars in Latin America
Cortex is the Internal Developer Portal eliminating “developer tax”…
Datasaur builds a data labeling workforce management platform for NLP.
Datree prevents Kubernetes misconfigurations from reaching production
Unified DevSecOps platform, helping developers ship good code.
Manage the words across your team’s product from design to production.
AI app builder for internal tools. Build back-office software faster…
Helps enterprises train college CS students on essential job skills
We are developing a drug to burn calories and increase metabolism…
Developing supersonic UAVs as a pathway to quiet supersonic flight
The easiest way to track, buy, and sell your company’s tech — all in…
Helping 100+ brands bring all quality and compliance operations…
India's first vegetable delivery service to restaurants with a hack
AI-powered gym and home workout planner that generates personalized plans, optimizes sets, reps, and weights based on user data.
Quickly build internal tools for your ops team's manual workflows
We are connecting every single Mexican to the financial system.
Glisten AI automatically categorizes and tags e-commerce product data using computer vision and natural language processing.
Marketplace enabling social commerce for brands and content creators.
Handl converts documents (invoices, income stabs, custom forms, etc.)…
We help job seekers quickly create resumes that get 2X more interviews
A talent acquisition software built for data-driven recruiting teams.
Homestead is a real estate development platform for homeowners
A developer experience platform that equips teams with tools to create exceptional customer experiences through superior documentation, API monitoring, and customizable developer dashboards.
We empower the world’s hiring teams to grow engaged, high-performing…
Jenfi provides revenue-based financing for digital businesses in Asia
AI-powered marketplace connecting gamers with professional players for coaching, carry services, and in-game companionship.
Modern egg freezing for half the cost in half the time with top docs
Building an AI Health Insurance Agent.
Menten AI designs peptide and protein therapeutics using quantum…
The Family AI - a copilot for parents to tackle the invisible load of…
Robotic Automation for cancer diagnostics - Robotic Microscopes &…
The only work management platform for both Human and AI Employees
Multiverse is a web-based game creation system inspired by Dungeons &…
ML models automatically monitor business metrics and send alerts for abnormal drops or spikes.
A competitive community of the brightest students in the world
The super simple stablecoin wallet with free transactions
Automated tooth cutting for dentists using imaging, AI and robotics
The social app for edge-of-culture communities
The single platform to analyze, test, observe, and deploy new features
Pulley helps founders and finance teams manage their equity and cap…
Dynamic sales materials that shape-shift based on the customers needs
Fullstack API and management platform for dashboards and reporting
The API to get recordings, transcripts, and metadata from meetings
Riya Collective is building the first community-driven global…
Affordable mental self-care for all. Acquired by Headspace Health.
Low-cost blood glucose test strips scanned with a smartphone camera…
AI platform for retail merchandising that optimizes inventory placement, re-balancing, and fulfillment decisions to maximize revenues.
StayQrious helps kids in India learn through online group classes,…
Building modern payments, accounting and cashflow management tools…
AI-enabled automation of diagnostic radiology workflow and reporting.
Long range, battery electric vertical take-off and landing aircraft.
Juno is ManusAI for controlling medical imaging& diagnostic device GUI
AI assistant that automates everyday tasks and streamlines workflows for professionals and businesses.
The Mercer Club is a subscription service that allows men to rent…
TrueNorth gives truckers a single place to manage their business.
AI for R&D of consumer brands like P&G to develop better products
A no-code website builder with a Notion-like interface that enables users to build and publish websites in minutes using AI-powered defaults and templates.
Helping Dropshippers in Colombia run the business and increase sales
Volumetric builds living multicellular tissues with a focus on the…
Route Optimisation platform for SMB in delivery & home services.
Generates synthetic training data for computer vision models using game engines and domain randomization.