176 startups in this batch
Summer 2019 was the peak of the pre-pandemic global expansion era, characterized by a massive push into international fintech and the rise of the "spreadsheet-killer." YC was aggressively funding founders who were digitizing legacy industries in Latin America and building high-touch SaaS for sectors that had previously resisted software.
This batch proved that verticalized operational software—like specialized medical billing and staff management for manufacturing—could command high ACVs by solving deep administrative pain. They validated a massive appetite for live data connectivity and point-of-sale financing, proving that users were ready to move away from static reports toward real-time, actionable business intelligence.
Many startups from this cohort struggled with the high operational overhead required to maintain manual data connectors and human-in-the-loop services. The assumption that "software + service" was the only way to scale broke when labor costs rose and the 2020 macro shift demanded higher margins. Today's builder should avoid the manual middleware trap that plagued 2019-era automation.
The "Actiondesk" vision of a live-data spreadsheet is now a natural language interface problem; builders can use LLMs to replace brittle SQL connectors with autonomous agents that fetch and analyze data. The 2026 wedge is building AI-native vertical ERPs that don't just record data for HR or finance but proactively execute the back-office tasks that S19 founders still had to hire teams for.
Arpeggio Bio develops drugs targeting transcription factors using AI…
Hearing aids that work in noisy places, like restaurants, using ML.
Blockstamp is an asset management software for industrial equipment
Gain Muscle and Shed Fat with a Digital Twin of Your Body
Modern healthcare for kids. Pediatric Primary, Urgent & Remote Care.
Compound is a wealth manager for people who work at tech companies.
The fastest way for developers to build notifications for their app.
Growth marketing platform offering courses, playbooks, and agency services to help startups build scalable growth engines.
EncepHeal develops medications to treat substance abuse, starting…
An e-commerce platform that delivers custom-fitted dresses tailored to women's exact body measurements with recommendations from body doubles.
Improve your browsing experience by staying organized and intentful
Customer data collection, safeguarding, & activation for healthcare
SaaS that helps renewables & energy storage operate more profitably
AI platform accelerating therapies for rare & inflammatory diseases.
An Open Source dependency security tool that is smarter than the rest
All-in-one health program helping seniors with their daily function
Building AI therapeutics for physical health conditions like IBS.
Api that let you connect all the restaurant tech services in Latam
The LatAm tech-enabled real estate broker to buy and sell houses.
The only platform that can prep data to answer EVERY question you…
Autonomous homebuilding factory for the $1.7 trillion housing crisis.
We help companies comply with privacy laws like GDPR. Many of these…
Making diverse, high-quality data easily available to anyone, anywhere
Open-source, design centric software for interacting with blockchains
Ramen VR is transforming game development with advanced XR + AI tools.
Discovering the true signals of disease to power life-changing drugs.
Shiru leverages ML to create proteins to feed the world sustainably.
We write ML software to more accurately select & price insurance risk.
Souffle Club:10x better LinkedIn alternative with profiles >> resumes
AI customer reputation & performance management for restaurant chains.
AI-powered productivity platform for task management, collaboration, automation, and building intelligent agents.
TaxProper helps large Real Estate owners manage their property taxes.
TRM is building a safer financial system for billions of people.
AI negotiation agent that helps companies save money on SaaS by using real contract data to benchmark prices and secure better deals.