145 startups in this batch
This cohort emerged during the "Agentic Pivot," a period where the initial hype of LLMs matured into autonomous execution within legacy industries. Macro conditions were defined by a "default alive" mandate, forcing founders to target high-ACV sectors like Insurance and Health Tech where operational inefficiencies were most acute.
The batch proved that verticalized AI agents could penetrate deep-stack enterprise workflows, moving beyond simple chat interfaces to handle complex tasks like COI generation and medical claim appeals. They validated a massive willingness to pay for deterministic AI workflows that replaced manual back-office labor in highly regulated environments.
Many startups in this era struggled when they focused too heavily on generic context retrieval without owning the underlying system of record. Builders today should learn that a "copilot" is often just a feature; the real value lies in full-stack automation that doesn't require a human-in-the-loop for every transaction.
The next wave belongs to solo builders creating multi-agent orchestration for niche industrial sectors like chemical engineering or supply chain logistics. By leveraging 2026-era reasoning models, you can automate the compliance and design loops that the S25 cohort first identified but couldn't fully solve with earlier LLMs.
AI-powered real-time compliance monitoring platform that detects and fixes medical documentation errors before they trigger claim denials or audits.
Data center infrastructure management software that monitors, controls, and optimizes data center operations through unified monitoring and AI-driven automation.
Cloud-based platform providing customizable AI agents and co-pilot for automating security investigations, detection engineering, and threat hunting.
Open source MCP integration platform for reliably tool use at scale.
Automatically write and update internal docs with every code commit.
Swarm robotics and full AI-command hierarchy integration
Automated document package parsing for investment & underwriting teams
Mortgage platform that automates the process to deliver lower rates and fees by cutting out intermediaries.
Evals and environments for computer use and software engineering work
Reinventing the trading terminal — one intelligent agent at a time.
Alfi - your group chat with social skills to bring friends closer
Affordable robotic workers
Program verification so even your systems engineers can vibecode
Automating complex legal workflows with human lawyers in the loop.
Tinfoil makes your AI workflows secure, verifiable, and private.
Open-source semi-humanoid dev kit → home data → autonomy → 20h/wk
AI powered email client that manages your email so you don't have to.